GPU acceleration of top genomics application with OpenACC

The OpenACC programming standard has enabled Chinese researchers to dramatically accelerate the DNADist genomics application, which is used in the early stages of development of treatments for genetic conditions, such as Down syndrome, hemophilia, cystic fibrosis, and sickle-cell disease.Sickle cell disease: Normal red blood cell (left) and sickled red blood cell (right)
Using the CAPS enterprise OpenACC compiler, Shanghai Jia Tong University researchers accelerated the DNADist application by 16 times on an NVIDIA Tesla GPU-based system by adding just four simple hints -- known as "directives" -- to the application code.

DNADist, a distance-matrix application for studying the genetic relationships between various species over evolutionary history, enables researchers to extract information from sequenced DNA data by reading nucleotide sequences, which may potentially lead to a greater understanding of the causes of and treatments for pervasive genetic diseases. Accelerating the DNADist application allows researchers to study a significantly larger range of input data and obtain actionable information earlier in the disease treatment research process.

A programming standard for parallel supercomputing using directives, OpenACC is designed to enable millions of researchers around the world to easily take advantage of the transformative power of GPU supercomputing. It provides the easiest way for users, with or without extensive parallel programming expertise, to accelerate their research in a matter of hours using familiar programming models.

Roche Impressed with OpenACC, Power of GPU Acceleration
By quickly delivering game-changing application acceleration with minimal effort, OpenACC provides world-leading pharmaceutical companies like Roche with the ability to research, identify and develop more effective drugs faster and more cost-effectively.

"I am astonished at how quickly and easily OpenACC unlocked the power of GPU acceleration for DNADist, which is one of our most critical applications," said Steve Pan, project director, Roche Pharma Global Informatics. "The potential impact of GPUs is priceless because getting our products to market faster, even one day earlier, will save more lives."

"Extracting meaningful information from the vast collection of available DNA sequencing data requires ever-increasing amounts of computational power," said Sumit Gupta, senior director of the Tesla business at NVIDIA. "OpenACC enables researchers to quickly and easily leverage the enormous performance of GPU accelerators to analyze mountains of genomics data. This dramatically reduces the time to study biological systems, and potentially leads to the development of more effective next-generation medicines."

A large and growing number of researchers and engineers are using OpenACC-supported compilers and hybrid CPU/GPU supercomputing systems to accelerate all types of applications, including CAD/CAM, image processing, materials science, molecular dynamics, quantum chemistry, and many other applications. In many cases, users are reporting that they have achieved as much as 5-10X or faster levels of acceleration in as little as a few hours of work.

Webinar to Showcase OpenACC, DNADist - Sept. 6, 2012
CAPS enterprise will deliver a free public webinar on Thursday, Sept. 6, 2012, to educate participants about OpenACC use cases and best practices, and provide more detail on the acceleration of the DNADist application. To learn more or to register, visit https://www2.gotomeeting.com/register/668751466.