ASTRONOMY

The Rosetta Resolver system is an enterprise bioinformatics solution for gene expression research developed by Rosetta Biosoftware and exclusively distributed by Agilent Technologies, Inc. (NYSE: A). The Rosetta Resolver system can be used with a variety of third party and internally developed DNA microarray technologies, including Agilent DNA microarrays. NIRS is a Japanese government institution focused on furthering the radiation health sciences and research on the medical use of radiation. "NIRS is committed to the development and advancement of radiation therapies to combat a variety of human cancers," said Dr. Takashi Imai, project leader of the Frontier Research Center at NIRS. "After conducting an extensive review of currently available enterprise microarray analysis solutions, we chose the Rosetta Resolver system as the software application to enhance our gene expression research. With the help of the Rosetta Resolver system, we intend to accelerate our efforts towards meeting clinical needs for radiation therapy of malignant tumors and radiation diagnostics of diseases." "Rosetta Biosoftware's mission is to provide cutting-edge bioinformatics solutions to aid in the discovery efforts of life science researchers worldwide," said Dr. Douglas E. Bassett, Jr., vice president and general manager of Rosetta Biosoftware. "The opportunity for us to enable NIRS' gene expression research efforts furthers our mission, and is accompanied by a strong investment on our behalf to grow our business in the Asia Pacific region. We are honored by the opportunity to work with one of Japan's finest research institutions." The Rosetta Resolver system is a high-capacity data storage, retrieval and analysis solution for gene expression data. The system is ideal for life science research organizations that need to assess compound specificity or toxicity, identify new genes or therapeutic targets, or compare and analyze large databases of expression profiles. The Rosetta Resolver system combines flexibility and ease of use with high-performance algorithms to produce an enterprise solution for rapid analysis of gene expression data. The Rosetta Resolver system can accept and analyze data from a wide variety of expression profiling formats, including Agilent DNA microarrays, and applies Rosetta Biosoftware's proprietary error models to yield quality statistics for every gene expression measurement within the system. These statistics are automatically leveraged by all of the Rosetta Resolver system analysis tools for reliable results. In addition to NIRS, life science research organizations that have licensed the Rosetta Resolver system include many of the top drug development companies in the world, such as Aventis Pharmaceuticals, Bristol-Myers Squibb, GlaxoSmithKline and Merck & Co., Inc., as well as premier academic institutions such as the Harvard University Center for Genomics Research.