Applied Biosystems Announces Enhancements To Celera Discovery System

FOSTER CITY, CA – Applied Biosystems Group (NYSE:ABI) an Applera Corporation business, announced a new release of the Celera Discovery System™ (CDS) online platform that includes enhanced visualization and analysis tools for comparing the human and mouse genomes, additional data integration, and a new subscription model for academic researchers. "The latest enhancements to CDS should enable subscribers to more easily apply comparative genomics to their discovery process and to better understand the roles of genes in the context of evolutionary conservation," said Deborah Smeltzer, Vice President of the Knowledge Business for Applied Biosystems. "Applied Biosystems and Celera Genomics have made significant investments in data aggregation, validation, curation, classification, quality assurance, and have further integrated public reference data. We believe our subscribers will save time and costs through online access to an integrated set of high-quality data and analysis tools that eliminate the need for data infrastructure development and maintenance." New subscriptions to the Celera Discovery System online platform will now be available to researchers at academic and non-profit institutions through a single-user, one-year subscription agreement. These researchers can easily begin the subscription process online through the CDS website, available at http://www.celeradiscoverysystem.com. Applied Biosystems and Celera Genomics are collaborating to integrate Celera's genomic and biological information with Applied Biosystems' products and services. CDS subscribers can now order the Applied Biosystems Assays-on-Demand™ products, ready-to-use, functionally validated assays for genotyping and gene expression analysis, within the context of their analysis results using CDS. The new release of CDS includes an updated interactive Map Viewer, which provides enhanced and customizable graphical displays for comparing human and mouse genes within their genomic context. The Map Viewer also now enables subscribers to conduct BLAST searches in batch mode and to customize views of data from the entire chromosome to the single nucleotide level. These enhancements are intended to facilitate high-throughput analysis and should enable subscribers to analyze biological relationships within any region of the human or mouse genomes. Additional Enhancements: Pre-computed human-mouse ortholog pairs displayed with synteny information and neighboring genes. The first release of annotated mouse genes, hand-curated by scientists from Celera Genomics. Annotation of human gene regulatory regions through mapping of transcription factor binding sites. Panther Universal Protein Library 3.1 protein classifications, which now contain 4,000 additional protein families and 12,000 subfamilies, providing more comprehensive functional predictions. Key literature references pertaining to the structure and function of genes and their products. An upgraded set of sequence analysis tools for data comparison, manipulation, and protein prediction. Links to the Human Gene Mutation Database (HGMD), Online Mendelian Inheritance in Man (OMIM), Swiss-Prot and LocusLink databases.