ZetaGrid is a grid-computing platform for solving large, computing-intensive problems that can be devided into loosely-coupled units. The interactions, performance, availability, and scalability of this technology are proven in multiple administrative domains involving more than 10,000 computers in a heterogeneous, dynamic environment. The first project of ZetaGrid was a mathematical one: the verification of the zeros of the zeta function (that's where the name "ZetaGrid" comes from).