SC06, the most important international conference for our community, will convene this fall in Tampa, Florida. This year the conference will take its inspiration from Albert Einstein who said "Computers are incredibly fast, accurate and stupid; humans are incredibly slow, inaccurate and brilliant; together they are powerful beyond imagination." Registration is open for SC06, the annual conference of high-performance computing, networking, storage and analysis. This year's meeting will convene November 11-17 at the Tampa Convention Center in our home-town state of Florida. Online registration information can be found at its Web site. To qualify for the advance registration discounts, registration and payment must be received by 5 pm (Eastern Time) Sunday, October 15. Media representatives should follow the “News & Press” links for registration at its Web site. This year's technical program includes 26 full and half-day tutorials, 54 technical papers, seven panel discussions, a series of Masterworks sessions, poster presentations and eight workshops. Visionaries and well-known leaders will speak on the state of high-performance computing in the keynote and plenary sessions, as well as participate in lively panel discussions. Several awards will be presented, including the prestigious Sidney Fernbach and Seymour Cray Engineering awards, the Gordon Bell Prizes for fastest computer performance, and challenge awards recognizing competitive efforts in utilizing bandwidth, analyzing and visualizing data, and effectively accessing stored data. An education program will offer hands-on sessions for teacher and faculty teams to help them incorporate computational tools into the classroom. SCinet, the conference's high-performance, production-quality network backbone, will use the most advanced technology to make the Tampa Convention Center one of the best-connected sites on the planet. The exhibition area of the Tampa Convention Center has been will feature displays by more than 225 industrial and research exhibitors showcasing their latest systems, services and scientific achievements. SC06 is sponsored by the Institute of Electrical and Electronics Engineers (IEEE) Computer Society and the Association for Computing Machinery's Special Interest Group on Computer Architecture (ACM SIGARCH). For more information, see its Web site.